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A group of researchers made random visits to 152 doctors' offices to see if they could get prescriptions for Paxil, an antidepressant drug, merely by requesting the drug by name. The results? More than fifty percent of those who asked for Paxil by name were not only written a prescription for the drug on the spot, they were also diagnosed with depression without showing a single symptom! My staff investigators continue to hear from FDA employees who believe in their agency and ...

Feed Your Genes Right: Eat to Turn Off Disease-Causing Genes and Slow Down Aging Jack Challem See book keywords and concepts

Jonathan Benjamin compared inositol to an antidepressant drug in 21 patients who had frequent panic attacks. After one month of taking 12 to 18 grams of inositol daily, patients had significantly fewer panic attacks. They also had fewer side effects compared with people taking the drug. To achieve Benjamin's 12 to 18 grams of inositol daily, you would have to take at least that many tablets or capsules. Your best source for such a product would be a compounding pharmacy, a drugstore that makes custom preparations.

Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements Phyllis A. Balch, CNC See book keywords and concepts

There is no FDA-approved treatment for fibromyalgia, but there are now two studies that indicate a majority of people who suffer from the disorder can find relief by taking duloxetine (Cymbalta), an antidepressant drug. A report on the latest study of the drug was reported in the medical journal Arthritis and Rheumatism. Duloxetine may be effective because it works by boosting levels of two neurotransmitters that play a role in pain processing.

The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D. See book keywords and concepts

Case reports on two bipolar patients treated with lithium or an antidepressant drug described marked improvements when they were given 12 grams daily of L-tryptophan.9,10 Two trials using 6 grams of L-tryptophan daily for acute mania in patients with bipolar disorder found little or no improvement,11' 12 but another double-blind, controlled study using 9.6 grams daily reported better results.13 L-tryptophan is converted to 5-hydroxytryptophan (page 459) (5-HTP) before it becomes serotonin in the body.

There have been five case reports of chromium (page 493) supplementation (200-400 meg per day) significantly improving mood in people with a type of depression called dysthymic disorder who were also taking the antidepressant drug sertraline (Zoloft).80 These case reports, while clearly limited and preliminary in scope, warrant further research to better understand the benefits, if any, of chromium supplementation in people with depression.

America Fooled: The Truth About Antidepressants, Antipsychotics and How We've Been Deceived Dr. Timothy Scott See book keywords and concepts

Truth should never be decided by a vote, by massive multi-million dollar advertising campaigns or by antidepressant drug studies designed and paid for by drug manufacturers. Truth should be decided by an honest, objective assessment of the evidence and by logic. It is not enough to say "I'm right" or "I'm right, and peer-reviewed research found in medical journals proves it." You need to have exact references to the facts which are used to support arguments and conclusions. This book contains over 1,800 references to some of the best of the scientific research.

The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D. See book keywords and concepts

Controlled trials101,102,103 have found electro-acupuncture (acupuncture accompanied by electrical currents) equally effective as antidepressant drug therapy without causing side effects. However, a controlled trial found that both real and fake acupuncture improved depression equally well compared to no treatment.104 It is well known that placebo effects are common in the treatment of depression,105 so more controlled trials are needed before accepting the usefulness of acupuncture for depression.

Disease Prevention and Treatment The Life Extension Editorial Staff See book keywords and concepts

An "old" drug frequently ptescribed to induce a state of deep sleep is a tricyclic antidepressant drug called Elavil (amittiptyline hydrochloride). This drug normally puts people to sleep fast, but induces many side effects such as severe dry mouth, weight gain, constipation, and a host of other problems. Newer tricyclic antidepressant drugs produce fewer side effects, but do not work as well in inducing deep sleep patterns. A typical dose of Elavil taken a few hours before bedtime is 10-25 mg.

The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D. See book keywords and concepts

In a double-blind trial, patients with bipolar disorder had greater improvement with a combination of 5-HTP at 300 mg daily plus an antidepressant drug than with 5-HTP alone.15 S-adenosylmethionine (page 583) (SAMe) is another amino acid that has an impact on serotonin levels, and it has demonstrated significant antidepressant effects in clinical trials.16,17'18 In both controlled and preliminary studies, SAMe has been shown to be helpful for the depressive symptoms of bipolar disorder. However, some patients have switched from depression to mania while using SAMe at 500 to 1,600 mg daily.

When combined with the tricyclic antidepressant drug imipramine (Tofranil), response rates were even higher (57.1%). For long-term management of panic disorder, imipramine produced a superior quality of response, but CBT had more durability and was better tolerated. ASTHMA What do I need to know? Self-care for asthma can be approached in a number of ways—but it can be hard to know just where to start.

One trial compared the effects of an exercise training program with those of a prescription antidepressant drug in people over 50 years of age.19 The researchers found the two approaches to be equally effective after 16 weeks of treatment. Nutritional supplements that may be helpful Iron deficiency (page 278) is known to affect mood and can exacerbate depression, but it can only be diagnosed and treated by a doctor. While iron deficiency is easy to fix with iron (page 540) supplements, people who have not been diagnosed with iron deficiency should not supplement iron.

Encyclopedia of Natural Medicine, Revised Second Edition Michael T. Murray, N.D., Joseph E. Pizzorno, N.D. See book keywords and concepts

In one of the more recent double-blind studies, forty older patients (ranging in age from fifty-one to seventy-eight years old) with depression who had not benefited fully from standard antidepressant drugs were given either 80 mg of Ginkgo biloba extract three times daily or a placebo along with their antidepressant drug.119 By the end of the fourth week of the study, the total average score on the Hamilton Depression Scale (HDS) was reduced from 14 to 7. At the end of the eighth week, the total score in the Ginkgo biloba extract group had dropped to 4.5.

Disease Prevention and Treatment The Life Extension Editorial Staff See book keywords and concepts

Adrafinil This is a European antidepressant drug that is being successfully used by Europeans and Americans who import it fot petsonal use. The dose is usually 2 tablets twice a day. Phenylalanine and Tyrosine Phenylalanine and tyrosine ate both amino acids. Out bodies can convett phenylalanine to tyrosine and phenylethylamine (PEA). Tyrosine is the precursor to several neurottansmitters, including norepinephrine and dopamine. PEA is found in high concentrations in chocolate, occuts naturally in the brain, and seems to elevate mood. Low urinary levels have been found in depressed patients.

If you wish to switch from an antidepressant drug to St. John's Wort, talk to your physician about safe ways to do this. St. John's Wort has been shown to diminish the effectiveness of a growing list of dmgs: digoxin, warfarin, phenprocoumon, cyclosporin, amitryptiline, theophylline, oral contraceptives, indinavir, and some anticancer dmgs. Primarily, it lowers the blood levels of these dmgs. How? Research suggests that active ingredients in the herb crank up the production of a liver enzyme called CYP3A, which breaks down a host of compounds, including many dmgs. In other words, St.

Amitriptyline is a tricyclic antidepressant drug with many side effects that preclude long-tetm use in most people. For refractive cases of MFS, a homeopathic solution of traumeel and/or a mild narcotic called buprinorphine injected into the trigger point(s) may be employed. Dt. Travell's technique of injecting corticosteroids and/or local anesthetics into the trigger points appears to be effective in reducing muscle pain. Dr. Iwama and his colleagues at the Central Aizu General Hospital, Aizu, Japan conducted studies on 40 women with chronic lumbar, shoulder, or neck myofascial pain.

Death By Prescription: The Shocking Truth Behind an Overmedicated Nation Ray Strand, M.D. See book keywords and concepts

Now there are reports that pharmacists have mistakenly given Prilosec for Prozac, an antidepressant drug. Other common mix-ups include • Aminophylline for Amitriptyline • Digoxin for digitoxin • Nicoderm for Nitroderm • Haldol for Halcion • Urax for Eurax • Xanax for Zantac5 You can see how easy it would be to confuse some of these names! According to the FDA, medication mix-ups cause roughly one death per day.6 Many of these errors lead to serious adverse drug reactions that lead even to hospitalization.

Water: For Health, for Healing, for Life: You're Not Sick, You're Thirsty! F. Batmanghelidj See book keywords and concepts

In the past, tryptophan itself was used in this capacity, before it was taken off the market and the deck was cleared for the introduction of an antidepressant drug called Prozac. While tryptophan makes more serotonin at a much cheaper cost, Prozac is touted to stop the rapid neutralization of serotonin once it is secreted at the nerve clefts. Why? Because people with depression have low brain-serotonin levels. Many of the problems in human physiology, and the establishment of stress in the body, are the consequence of the disproportionate transfer of some materials into the brain.

The ABC Clinical Guide to Herbs Mark Blumenthal See book keywords and concepts

John's wort and antidepressant drug interactions in the elderly./ Geriatr Psychiatry Neurol 1999; 12:7-10. Lavie G, MazurY, Lavie D, etal. Hypericin as an antiretroviral agent. Annals NY Acad Sci 1990; 616:556-62. Lehrl S, et al. Results from measurements of the cognitive capacity in patients during treatment with Hypericum extract. Nervenheikunde 1993; 12:268-366. Lenoir S, Degenring F, Sailer R. A double-blind randomized trial to investigate three different concentrations of a standardized fresh plant extract obtained from the shoot tips of Hypericum perforatum L.

Food & Mood: The Complete Guide to Eating Well and Feeling Your Best, Second Edition Elizabeth Somer, M.A., R.D. See book keywords and concepts

For example, in a Scandinavian study, tryptophan was as effective as the antidepressant drug imipramine, and had fewer side effects. Other studies report similar results; sometimes the tryptophan was longer lasting than the usual pharmacologic treatment. But don't go looking for tryptophan tablets, because you won't find them. The Food and Drug Administration (FDA) banned tryptophan supplements from the market in 1989 after an outbreak of a rare disorder called eosinophilia-myalgia syndrome was linked to taking contaminated tryptophan pills.

Smart Medicine for Healthier Living : Practical A-Z Reference to Natural and Conventional Treatments for Adults Janet Zand, LAc, OMD, Allan N. Spreed, MD, CNC, James B. LaValle, RPh, ND See book keywords and concepts

This is an antidepressant drug with potential side effects that include drowsiness, low blood pressure, insomnia, nausea, headache, jerky movements, jaundice, and bone-marrow depression. DIETARY GUIDELINES ¦ It is important not to eat too much at mealtimes. Many people with narcolepsy find that if they eat five small meals each day rather than three larger ones, they can handle their sleepiness better. Keeping blood-sugar levels relatively even throughout the day makes it easier to remain awake. ¦ Focus on protein foods during the day.

Principles and Practice of Phytotherapy: Modern Herbal Medicine Simon Mills and Kerry Bone See book keywords and concepts

In an uncontrolled trial, Ginkgo extract (average dose 207 mg/day) was found to be 84% effective in alleviating sexual dysfunction secondary to antidepressant drug use in 33 female and 30 male patients.128 No adverse effects were reported. TOXICOLOGY Standardized Ginkgo extract had an LD50 value of 7.7 g/kg in mice (oral). Chronic toxicity studies over 27 weeks, at an initial dose of 20 and 100 mg/kg /day gradually increasing to 400 and 500 mg/kg/day, showed no evidence of organ damage and no impairment of hepatic or renal function.

Prescription Medicines, Side Effects and Natural Alternatives American Medical Publishing See book keywords and concepts

Six years later, a jury found that there was no reason to blame the popular antidepressant drug or its manufacturer, Eli Lilly & Co., for the carnage. It was Wesbecker's mental illness, they ruled, and not the medication, that fueled his attack. Even though the judge later discovered that a secret settlement had been reached before the case even went to the jury, the case still had "a chilling effect" on future lawsuits, says Houston attorney Arnold "Andy" Vickery. "With the exception of me, I don't know anybody who's taking on new cases against these drug companies. It's a monumental effort.

The Encyclopedia of Popular Herbs Robert S. McCaleb, Evelyn Leigh, and Krista Morien See book keywords and concepts

John's wort with those of the synthetic tricyclic antidepressant drug imipramine in people with severe depression showed that the two test substances were comparable in effectiveness for patients with severe depression (see Specific Studies). Because the patients were severely depressed, the investigators used dosages of St. John's wort and imipramine that were twice as high as those used in earlier trials.5 The results of this study are promising, but more research is needed before St. John's wort can be recommended for people with severe depression.

John's wort extract produced benefits comparable to those of the tricyclic antidepressant drug imipramine, but with far fewer side effects. The 209 participants in the trial were randomly divided into two groups: one group received treatment with 600 mg St. John's wort extract three times a day, and the other took 50 mg imipramine three times a day. The 1,800-mg daily dose of St. John's wort extract used in the study and the 150-mg dose of imipramine were both twice as high as doses used in earlier trials that compared the two substances.

John's wort extract at a total daily dose of 900 mg was as helpful as the sedating tricyclic antidepressant drug amitriptyline (25 mg three times daily) in relieving symptoms in 165 people with mild to moderate depression. According to results of the randomized controlled study, there was no statistically significant difference in effectiveness between the two study groups, although the amitriptyline group demonstrated a tendency toward a better response rate. However, there was a significant difference between the groups with regard to adverse effects.

John's wort was just as effective as the antidepressant drug amitriptyline in treating symptoms of depression—with far fewer side effects. The multicenter, randomized, double-blind study involved 130 depressed people who took either 1 capsule of the herbal formula three times daily or 1 (25 mg) capsule of amitriptyline three times daily over a 6-week period. After 4 days of treatment, the dosage for both therapies was increased to 2 capsules three times daily, for 9 participants in the herb group and 5 in the antidepressant group.

Viral Immunity J. E. Williams, O.M.D. See book keywords and concepts

The most common form of treatment is an antidepressant drug which, of course, does nothing for the fatigue unless it is directly associated with clinical depression. There is an easy way to assess fatigue. In depressed patients, if they push themselves to exercise, they feel not only less depressed but also have more energy. On the other hand, when the pathologically-fatigued patient tries to exercise, even slight exertion worsens the exhaustion, often putting them to bed for days.

The Omega-3 Connection: The Groundbreaking Anti-depression Diet and Brain Program Andrew L. Stoll See book keywords and concepts

Working backward, scientists then try to determine which biochemical mechanisms in the brain are influenced by the antidepressant drug. For example, if a new and effective antidepressant affects the neurotransmitter serotonin, then it is reasonable to assume that serotonin must be involved somehow in major depression. A more detailed picture may emerge from animal studies, where analyzing brain chemistry is easier and more direct than it is in humans. The omega-3 fatty acids are an integral part of the structure and function of the brain.

The Serotonin Solution Judith J. Wurtman and Susan Suffes See book keywords and concepts

Recent reports have suggested that women with PMS who suffer debilitating changes in mood can be helped by the antidepressant drug Prozac, because of its role in restoring serotonin activity to normal. Other medications, such as Zoloft and Paxil, are also now being tested for use in alleviating PMS. It is even possible that the weight-loss drug dexfenfluramine (Redux) may eventually be used as well. Dr. Am-non Brzenzinski of Hebrew University/Hadassah Medical School and I have done studies to show that Redux works both to diminish premenstrual depression and to curb excessive appetite.

Radical Healing: Integrating the World's Great Therapeutic Traditions to Create a New Transformative Medicine Rudolph M. Ballentine, M.D. See book keywords and concepts

FIGURE 141 mon example is the allure of the antidepressant drug. It promises respite and creates the illusion that all is well. But when it's discontinued, the feelings reemerge because the drug has failed to move us through the expansion of consciousness that would ultimately bring us out of this circular impasse. THE VICIOUS CIRCLE AND HOW TO GET OUT OF IT Another desperate tactic to escape depression is to deal with the negative pole of what has been projected and take on the Bad Guys—simply quit running away and face their wrath.

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